The tightly regulated copper window in yeast.
نویسندگان
چکیده
The two opposing yeast copper regulators, Ace1 and Mac1, were converted into two fluorescent probes, Ace1-FRET and Mac1-FRET, which selectively and sensitively respond to Cu(+). The Cu(+)-binding curves obtained for both regulators as well as for the copper storage proteins Cup1 and Crs5 show that free copper(i) is maintained in a narrow window inside yeast.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 9 شماره
صفحات -
تاریخ انتشار 2011